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• 02:27, 2 February 2026 Afference talk contribs created page Progesterone (Created page with "'''Progesterone''' is a female sex hormone, responsible for managing parts of the menstrual cycle. In feminizing gender-affirming hormone therapy, it has been claimed to help with breast size, sexual desire, and mood, but there is a lack of scientific evidence for these claims. Oral progesterone also has bioavailability problems, and in order to derive any possible benefit from progesterone, you need to take it rectally (it is an oral medication but it's fine to take...")